Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy

Antibody-based biologics are the corner stone of modern immunomodulatory therapy. Though highly effective in dampening systemic inflammatory processes, their large size and Fc-fragment mediated effects hamper crossing of the blood brain barrier (BBB). Nanobodies (Nbs) are single domain antibodies de...

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Detalles Bibliográficos
Autores principales: Jank, Larissa, Pinto-Espinoza, Carolina, Duan, Yinghui, Koch-Nolte, Friedrich, Magnus, Tim, Rissiek, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640704/
https://www.ncbi.nlm.nih.gov/pubmed/31544811
http://dx.doi.org/10.3390/antib8010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640704/
https://www.ncbi.nlm.nih.gov/pubmed/31544811
http://dx.doi.org/10.3390/antib8010005

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