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Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy
Antibody-based biologics are the corner stone of modern immunomodulatory therapy. Though highly effective in dampening systemic inflammatory processes, their large size and Fc-fragment mediated effects hamper crossing of the blood brain barrier (BBB). Nanobodies (Nbs) are single domain antibodies de...
Autores principales: | Jank, Larissa, Pinto-Espinoza, Carolina, Duan, Yinghui, Koch-Nolte, Friedrich, Magnus, Tim, Rissiek, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640704/ https://www.ncbi.nlm.nih.gov/pubmed/31544811 http://dx.doi.org/10.3390/antib8010005 |
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