Binding of Immunoglobulin G to Protoporphyrin IX and Its Derivatives: Evidence the Fab Domain Recognizes the Protoporphyrin Ring

Immunoglobulin G (IgG) is known to bind zinc via the Fc domain. In this study, biotinylated protoporphyrin IX (PPIX) was incubated with human IgG and then zinc-immobilized Sepharose beads (Zn-beads) were added to the mixture. After washing the beads, the binding of biotinylated PPIX with IgG trapped...

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Detalles Bibliográficos
Autor principal: Orino, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640705/
https://www.ncbi.nlm.nih.gov/pubmed/31544812
http://dx.doi.org/10.3390/antib8010006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640705/
https://www.ncbi.nlm.nih.gov/pubmed/31544812
http://dx.doi.org/10.3390/antib8010006

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