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Synthesis of 2-Tetrazolylmethyl-isoindolin-1-ones via a One-Pot Ugi-Azide/(N-Acylation/exo-Diels–Alder)/Dehydration Process

[Image: see text] A series of fifteen 2-tetrazolylmethyl-isoindolin-1-one linked-type bis-heterocycles were synthesized in 10–76% yields under mild conditions via a one-pot Ugi-azide/(N-acylation/exo-Diels–Alder)/dehydration process from furan-2-ylmethanamine, aldehydes, isocyanides, azidotrimethyls...

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Detalles Bibliográficos
Autores principales: Rentería-Gómez, Angel, Islas-Jácome, Alejandro, Cruz-Jiménez, Alicia E., Manzano-Velázquez, Jessica C., Rojas-Lima, Susana, Jiménez-Halla, J. Oscar C., Gámez-Montaño, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640813/
https://www.ncbi.nlm.nih.gov/pubmed/31457175
http://dx.doi.org/10.1021/acsomega.6b00281