N-Alkylation and Aminohydroxylation of 2-Azidobenzenesulfonamide Gives a Pyrrolobenzothiadiazepine Precursor Whereas Attempted N-Alkylation of 2-Azidobenzamide Gives Benzotriazinones and Quinazolinones

[Image: see text] N-Alkylation of 2-azidobenzenesulfonamide with 5-bromopent-1-ene gave an N-pentenyl sulfonamide, which underwent intramolecular aminohydroxylation to give an N-(2-azidoaryl)sulfonyl prolinol, a precursor for the synthesis of a pyrrolobenzothiadiazepine. The attempted N-alkylation o...

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Detalles Bibliográficos
Autores principales: Hamasharif, Muslih S., Smith, Oliver E. P., Curran, Collette J., Hemming, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640974/
https://www.ncbi.nlm.nih.gov/pubmed/31457499
http://dx.doi.org/10.1021/acsomega.7b00211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640974/
https://www.ncbi.nlm.nih.gov/pubmed/31457499
http://dx.doi.org/10.1021/acsomega.7b00211

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