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Brønsted Acid-Catalyzed Epimerization-Free Preparation of Dual-Protected Amino Acid Derivatives

[Image: see text] An organocatalytic protocol, employing the commercially available EDC as coupling agent, has been developed for the preparation of dual-protected amino acid derivatives without epimerization. This methodology was then applied to different Boc-amino acid and amine derivatives in mod...

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Detalles Bibliográficos
Autores principales: de Castro, Pedro P., Rimulo, Isabela M. R., de Almeida, Angelina M., Diniz, Renata, Amarante, Giovanni W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641006/
https://www.ncbi.nlm.nih.gov/pubmed/31457632
http://dx.doi.org/10.1021/acsomega.7b00523