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Nanodisc-to-Nanofiber Transition of Noncovalent Peptide–Phospholipid Assemblies

[Image: see text] We report a novel molecular architecture of peptide–phospholipid coassemblies. The amphiphilic peptide Ac-18A-NH(2) (18A), which was designed to mimic apolipoprotein α-helices, has been shown to form nanodisc structures with phospholipid bilayers. We show that an 18A peptide cystei...

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Detalles Bibliográficos
Autores principales: Ikeda, Keisuke, Horiuchi, Ayame, Egawa, Ayako, Tamaki, Hajime, Fujiwara, Toshimichi, Nakano, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641012/
https://www.ncbi.nlm.nih.gov/pubmed/31457628
http://dx.doi.org/10.1021/acsomega.7b00424