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Copper(I)-Catalyzed 1,3-Dipolar Cycloaddition of Ketonitrones to Dialkylcyanamides: A Step toward Sustainable Generation of 2,3-Dihydro-1,2,4-oxadiazoles

[Image: see text] Cu(I)-catalyzed cycloaddition (CA) of the ketonitrones, Ph(2)C=N(+)(R′)O(–) (R′ = Me, CH(2)Ph), to the disubstituted cyanamides, NCNR(2) (R = Me(2), Et(2), (CH(2))(4), (CH(2))(5), (CH(2))(4)O, C(9)H(10), (CH(2)Ph)(2), Ph(Me)), gives the corresponding 5-amino-substituted 2,3-dihydro...

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Detalles Bibliográficos
Autores principales: Melekhova, Anna A., Smirnov, Andrey S., Novikov, Alexander S., Panikorovskii, Taras L., Bokach, Nadezhda A., Kukushkin, Vadim Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641119/
https://www.ncbi.nlm.nih.gov/pubmed/31457510
http://dx.doi.org/10.1021/acsomega.7b00130