Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census

Genomics and genome screening are proving central to the study of cancer. However, a good appreciation of the protein structures coded by cancer genes is also invaluable, especially for the understanding of functions, for assessing ligandability of potential targets, and for designing new drugs. To...

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Detalles Bibliográficos
Autores principales: Malhotra, Sony, Alsulami, Ali F., Heiyun, Yang, Ochoa, Bernardo Montano, Jubb, Harry, Forbes, Simon, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641202/
https://www.ncbi.nlm.nih.gov/pubmed/31323058
http://dx.doi.org/10.1371/journal.pone.0219935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641202/
https://www.ncbi.nlm.nih.gov/pubmed/31323058
http://dx.doi.org/10.1371/journal.pone.0219935

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