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Preparation of Phosphonic Acid Analogues of Proline and Proline Analogues and Their Biological Evaluation as δ(1)-Pyrroline-5-carboxylate Reductase Inhibitors

[Image: see text] Racemic 1-hydroxy-3-butenyl-, 3-chloro-1-hydroxypropyl-, and 3-bromo-1-hydroxypropylphosphonate and the corresponding (S)-enantiomers obtained by lipase-catalyzed resolution of the respective racemic chloroacetates were subjected to functional group manipulations. These comprised o...

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Detalles Bibliográficos
Autores principales: Qian, Renzhe, Kalina, Thomas, Horak, Jeannie, Giberti, Samuele, Forlani, Giuseppe, Hammerschmidt, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641291/
https://www.ncbi.nlm.nih.gov/pubmed/31458671
http://dx.doi.org/10.1021/acsomega.8b00354