Effect of Dimethyl Sulfoxide on the Binding of 1-Adamantane Carboxylic Acid to β- and γ-Cyclodextrins

[Image: see text] Most therapeutic targets are proteins whose binding sites are hydrophobic cavities. For this reason, the majority of drugs under development are hydrophobic molecules exhibiting low solubility in water. To tackle this issue, a few percent of cosolvent, such as dimethyl sulfoxide (D...

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Detalles Bibliográficos
Autores principales: Senac, Caroline, Desgranges, Stéphane, Contino-Pépin, Christiane, Urbach, Wladimir, Fuchs, Patrick F. J., Taulier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641370/
https://www.ncbi.nlm.nih.gov/pubmed/31457945
http://dx.doi.org/10.1021/acsomega.7b01212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641370/
https://www.ncbi.nlm.nih.gov/pubmed/31457945
http://dx.doi.org/10.1021/acsomega.7b01212

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