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Sulfurization of H-Phosphonate Diesters by Elemental Sulfur under Aqueous Conditions
[Image: see text] To assess the plausibility of prebiotic nucleic acid polymerization by a sequential phosphitylation–sulfurization mechanism, the rates of hydrolysis and sulfurization of bis(2′,3′-O-methyleneadenosin-5′-yl)-H-phosphonate, a dinucleoside H-phosphonate diester, have been determined o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641597/ https://www.ncbi.nlm.nih.gov/pubmed/31457787 http://dx.doi.org/10.1021/acsomega.7b00970 |