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Systematic Functional Analysis of Active-Site Residues in l-Threonine Dehydrogenase from Thermoplasma volcanium

[Image: see text] Enzymes have been through millions of years of evolution during which their active-site microenvironments are fine-tuned. Active-site residues are commonly conserved within protein families, indicating their importance for substrate recognition and catalysis. In this work, we syste...

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Detalles Bibliográficos
Autores principales: Desjardins, Morgan, Mak, Wai Shun, O’Brien, Terrence E., Carlin, Dylan Alexander, Tantillo, Dean J., Siegel, Justin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641618/
https://www.ncbi.nlm.nih.gov/pubmed/31457655
http://dx.doi.org/10.1021/acsomega.7b00519