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Systematic Functional Analysis of Active-Site Residues in l-Threonine Dehydrogenase from Thermoplasma volcanium
[Image: see text] Enzymes have been through millions of years of evolution during which their active-site microenvironments are fine-tuned. Active-site residues are commonly conserved within protein families, indicating their importance for substrate recognition and catalysis. In this work, we syste...
Autores principales: | Desjardins, Morgan, Mak, Wai Shun, O’Brien, Terrence E., Carlin, Dylan Alexander, Tantillo, Dean J., Siegel, Justin B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641618/ https://www.ncbi.nlm.nih.gov/pubmed/31457655 http://dx.doi.org/10.1021/acsomega.7b00519 |
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