Theoretical Study on the Epimerization of Azlactone Rings: Keto–Enol Tautomerism or Base-Mediated Racemization?

[Image: see text] Azlactones are versatile heterocycles employed in a diversity of transformations; the main drawback of these cycles consists in the epimerization of the α-carbonyl stereocenter during its preparation. We hereby present a theoretical study to explain how the racemization occurs. Two...

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Detalles Bibliográficos
Autores principales: de Castro, Pedro P., Batista, Gabriel M. F., dos Santos, Hélio F., Amarante, Giovanni W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641619/
https://www.ncbi.nlm.nih.gov/pubmed/31458601
http://dx.doi.org/10.1021/acsomega.8b00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641619/
https://www.ncbi.nlm.nih.gov/pubmed/31458601
http://dx.doi.org/10.1021/acsomega.8b00060

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