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Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or α-synuclein, is localized to the mitochondrial matrix

Several proteins linked to familial Parkinson disease have been associated with mitochondrial (dys-)function and have been described to reside within mitochondria. The putative mitochondrial and sub-mitochondrial localization of these proteins remains disputed, however, potentially due to conflictin...

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Detalles Bibliográficos
Autores principales: Osuagwu, Nelson, Dölle, Christian, Tzoulis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641658/
https://www.ncbi.nlm.nih.gov/pubmed/31323073
http://dx.doi.org/10.1371/journal.pone.0219909