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Mutagenesis Reveals an Unusual Combination of Guanines in RNA G-Quadruplex Formation

[Image: see text] The classic G-quadruplex motif consists of a continuous array of 3–4 guanine residues with an intermittent loop size of 1–7 nucleotides (G(3–4)N(1–7)G(3–4)N(1–7)G(3–4)N(1–7)G(3–4)). An RNA G-quadruplex is able to attain only one parallel G-quadruplex topology owing to steric constr...

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Detalles Bibliográficos
Autores principales: Agarwala, Prachi, Pal, Gargi, Pandey, Satyaprakash, Maiti, Souvik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641730/
https://www.ncbi.nlm.nih.gov/pubmed/31457759
http://dx.doi.org/10.1021/acsomega.7b00377