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Anti-addition of Dimethylsulfoxonium Methylide to Acyclic α,β-Unsaturated Ketones and Its Application in Formal Synthesis of an Eicosanoid

[Image: see text] Cyclopropanation using dimethylsulfoxonium methylide (Corey–Chaykovsky reaction) was examined with a series of linear α,β-unsaturated ketones, and the results showed that the major trajectory for the addition of the sulfur ylide to the enones is anti, related to the γ-substituent....

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Detalles Bibliográficos
Autores principales: Angamuthu, Venkatachalam, Chang, Wen-Jung, Hou, Duen-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641733/
https://www.ncbi.nlm.nih.gov/pubmed/31457710
http://dx.doi.org/10.1021/acsomega.7b00663