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A Small Molecule Inhibitor of Bruton’s Tyrosine Kinase Involved in B-Cell Signaling

[Image: see text] Protein kinases are fundamental within almost all cellular signal transduction networks. Among these, Bruton’s tyrosine kinase (Btk), which belongs to the Tec family of proteins, plays an imperative part in B-cell signaling. Owing to its role, Btk has been established as an importa...

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Detalles Bibliográficos
Autores principales: Ratzon, Einav, Bloch, Itai, Nicola, Meshel, Cohen, Elad, Ruimi, Nili, Dotan, Nesly, Landau, Meytal, Gal, Maayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641755/
https://www.ncbi.nlm.nih.gov/pubmed/31457731
http://dx.doi.org/10.1021/acsomega.7b00576