Facile Synthesis of Dabigatran Etexilate Mesylate, an Anticoagulant Drug, Using a Novel Synthon, N-Hexyl-4-nitrophenyl Carbonate

[Image: see text] Facile synthesis for Dabigatran etexilate mesylate (1), an anticoagulant drug, is reported using a novel synthon, n-hexyl-4-nitrophenyl carbonate (32), which substantially eliminates the formation of potential impurities 20–27, which were generated due to the use of n-hexyl chlorof...

Descripción completa

Detalles Bibliográficos
Autores principales: Solanki, Pavankumar V., Uppelli, Sekhar Babu, Patil, Ravin B., Dhokrat, Pramod A., Bembalkar, Saroj R., Mathad, Vijayavitthal T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641937/
https://www.ncbi.nlm.nih.gov/pubmed/31458774
http://dx.doi.org/10.1021/acsomega.8b00846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641937/
https://www.ncbi.nlm.nih.gov/pubmed/31458774
http://dx.doi.org/10.1021/acsomega.8b00846

Ejemplares similares