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Glycosylation of acyl carrier protein-bound polyketides during pactamycin biosynthesis

Glycosylation is a common modification reaction in natural products biosynthesis and has been known to be a post assembly line tailoring process in glycosylated polyketide biosynthesis. Here, we show that in pactamycin biosynthesis glycosylation can take place on an acyl carrier protein (ACP)-bound...

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Detalles Bibliográficos
Autores principales: Eida, Auday A., Abugrain, Mostafa E., Brumsted, Corey J., Mahmud, Taifo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642016/
https://www.ncbi.nlm.nih.gov/pubmed/31308531
http://dx.doi.org/10.1038/s41589-019-0314-6