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The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment

Background: Immunotherapies targeting immune checkpoint proteins CTLA-4, PD-1, and PD-L1 have saved lives, but these therapies have only been effective in some patients. Patients positive for expression of immune checkpoint proteins in the tumor microenvironment show better response to immune checkp...

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Detalles Bibliográficos
Autores principales: Gaffney, Stephen G., Perry, Elizabeth B., Chen, Ping-Min, Greenstein, Andrew, Kaech, Susan M., Townsend, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642048/
https://www.ncbi.nlm.nih.gov/pubmed/31360302
http://dx.doi.org/10.18632/oncotarget.27027