Altered glutamatergic response and functional connectivity in treatment resistant schizophrenia: the effect of riluzole and therapeutic implications

RATIONALE: Anterior cingulate cortex (ACC) glutamatergic abnormalities are reported in treatment-resistant schizophrenia (TRS) and implicated in functional dysconnectivity and psychopathology. Preclinical evidence indicates riluzole reduces synaptic glutamate. However, it is unknown whether riluzole...

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Detalles Bibliográficos
Autores principales: Pillinger, Toby, Rogdaki, Maria, McCutcheon, Robert A., Hathway, Pamela, Egerton, Alice, Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642056/
https://www.ncbi.nlm.nih.gov/pubmed/30820633
http://dx.doi.org/10.1007/s00213-019-5188-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642056/
https://www.ncbi.nlm.nih.gov/pubmed/30820633
http://dx.doi.org/10.1007/s00213-019-5188-5

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