Regulation of lactate production through p53/β-enolase axis contributes to statin-associated muscle symptoms

BACKGROUND: Statin-associated muscle symptoms (SAMS) are the major adverse effects of the class of widely used lipid-lowering agents, and the underlying mechanism remains elusive. In this study, we investigated the potential contribution and molecular mechanism of increased lactate production to SAM...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jiajun, Du, Jingjing, Lin, Wanjun, Long, Ze, Zhang, Na, Huang, Xiaoming, Xie, Ying, Liu, Liang, Ma, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642070/
https://www.ncbi.nlm.nih.gov/pubmed/31201144
http://dx.doi.org/10.1016/j.ebiom.2019.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642070/
https://www.ncbi.nlm.nih.gov/pubmed/31201144
http://dx.doi.org/10.1016/j.ebiom.2019.06.003

Ejemplares similares