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The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammation

BACKGROUND: The Single immunoglobin interleukin-1 (IL-1)-related receptor (Sigirr), also known as IL-1R8, has been shown to exhibit broad anti-inflammatory effects against inflammatory diseases including acute lung injury, while molecular regulation of IL-1R8/Sigirr protein stability has not been re...

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Detalles Bibliográficos
Autores principales: Li, Lian, Wei, Jianxin, Li, Shuang, Jacko, Anastasia M., Weathington, Nathaniel M., Mallampalli, Rama K., Zhao, Jing, Zhao, Yutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642080/
https://www.ncbi.nlm.nih.gov/pubmed/31204278
http://dx.doi.org/10.1016/j.ebiom.2019.06.011