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Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using exogenous antigens and adoptive cells, we show a concept of utilizing biologically reprogrammed cytomembranes of the fused cells (FCs) derived from dendritic cells (DCs) and cancer cells as tumor vaccines....

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Detalles Bibliográficos
Autores principales: Liu, Wen-Long, Zou, Mei-Zhen, Liu, Tao, Zeng, Jin-Yue, Li, Xue, Yu, Wu-Yang, Li, Chu-Xin, Ye, Jing-Jie, Song, Wen, Feng, Jun, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642123/
https://www.ncbi.nlm.nih.gov/pubmed/31324770
http://dx.doi.org/10.1038/s41467-019-11157-1