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Epitope targeting with self-assembled peptide vaccines

Nanoparticle-based delivery systems are being used to simplify and accelerate new vaccine development. Previously, we described the solid-phase synthesis of a 61-amino acid conjugate vaccine carrier comprising a α-helical domain followed by two universal T cell epitopes. Circular dichroism, analytic...

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Detalles Bibliográficos
Autores principales: Zeigler, David F., Gage, Emily, Roque, Richard, Clegg, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642127/
https://www.ncbi.nlm.nih.gov/pubmed/31341647
http://dx.doi.org/10.1038/s41541-019-0125-5