Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions

The Satb1 genome organizer regulates multiple cellular and developmental processes. It is not yet clear how Satb1 selects different sets of targets throughout the genome. Here we have used live-cell single molecule imaging and deep sequencing to assess determinants of Satb1 binding-site selectivity....

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Detalles Bibliográficos
Autores principales: Ghosh, Rajarshi P., Shi, Quanming, Yang, Linfeng, Reddick, Michael P., Nikitina, Tatiana, Zhurkin, Victor B., Fordyce, Polly, Stasevich, Timothy J., Chang, Howard Y., Greenleaf, William J., Liphardt, Jan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642133/
https://www.ncbi.nlm.nih.gov/pubmed/31324780
http://dx.doi.org/10.1038/s41467-019-11118-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642133/
https://www.ncbi.nlm.nih.gov/pubmed/31324780
http://dx.doi.org/10.1038/s41467-019-11118-8

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