Boosting NAD(+) with a small molecule that activates NAMPT

Pharmacological strategies that boost intracellular NAD(+) are highly coveted for their therapeutic potential. One approach is activation of nicotinamide phosphoribosyltransferase (NAMPT) to increase production of nicotinamide mononucleotide (NMN), the predominant NAD(+) precursor in mammalian cells...

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Detalles Bibliográficos
Autores principales: Gardell, Stephen J., Hopf, Meghan, Khan, Asima, Dispagna, Mauro, Hampton Sessions, E., Falter, Rebecca, Kapoor, Nidhi, Brooks, Jeanne, Culver, Jeffrey, Petucci, Chris, Ma, Chen-Ting, Cohen, Steven E., Tanaka, Jun, Burgos, Emmanuel S., Hirschi, Jennifer S., Smith, Steven R., Sergienko, Eduard, Pinkerton, Anthony B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642140/
https://www.ncbi.nlm.nih.gov/pubmed/31324777
http://dx.doi.org/10.1038/s41467-019-11078-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642140/
https://www.ncbi.nlm.nih.gov/pubmed/31324777
http://dx.doi.org/10.1038/s41467-019-11078-z

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