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Boosting NAD(+) with a small molecule that activates NAMPT

Pharmacological strategies that boost intracellular NAD(+) are highly coveted for their therapeutic potential. One approach is activation of nicotinamide phosphoribosyltransferase (NAMPT) to increase production of nicotinamide mononucleotide (NMN), the predominant NAD(+) precursor in mammalian cells...

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Detalles Bibliográficos
Autores principales:	Gardell, Stephen J., Hopf, Meghan, Khan, Asima, Dispagna, Mauro, Hampton Sessions, E., Falter, Rebecca, Kapoor, Nidhi, Brooks, Jeanne, Culver, Jeffrey, Petucci, Chris, Ma, Chen-Ting, Cohen, Steven E., Tanaka, Jun, Burgos, Emmanuel S., Hirschi, Jennifer S., Smith, Steven R., Sergienko, Eduard, Pinkerton, Anthony B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642140/ https://www.ncbi.nlm.nih.gov/pubmed/31324777 http://dx.doi.org/10.1038/s41467-019-11078-z

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