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The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome

Abacavir is an antiretroviral drug used to reduce human immunodeficiency virus (HIV) replication and decrease the risk of developing acquired immune deficiency syndrome (AIDS). However, its therapeutic value is diminished by the fact that it is associated with drug hypersensitivity reactions in up t...

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Detalles Bibliográficos
Autores principales: Fodor, James, Riley, Blake T., Kass, Itamar, Buckle, Ashley M., Borg, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642150/
https://www.ncbi.nlm.nih.gov/pubmed/31324847
http://dx.doi.org/10.1038/s41598-019-47001-1