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The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome
Abacavir is an antiretroviral drug used to reduce human immunodeficiency virus (HIV) replication and decrease the risk of developing acquired immune deficiency syndrome (AIDS). However, its therapeutic value is diminished by the fact that it is associated with drug hypersensitivity reactions in up t...
Autores principales: | Fodor, James, Riley, Blake T., Kass, Itamar, Buckle, Ashley M., Borg, Natalie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642150/ https://www.ncbi.nlm.nih.gov/pubmed/31324847 http://dx.doi.org/10.1038/s41598-019-47001-1 |
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