Cargando…

Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

Innate lymphoid cells (ILCs) play strategic roles in tissue homeostasis and immunity. ILCs arise from lymphoid progenitors undergoing lineage restriction and the development of specialized ILC subsets. We generated “5x polychromILC” transcription factor reporter mice to delineate ILC precursor state...

Descripción completa

Detalles Bibliográficos
Autores principales: Walker, Jennifer A., Clark, Paula A., Crisp, Alastair, Barlow, Jillian L., Szeto, Aydan, Ferreira, Ana C.F., Rana, Batika M.J., Jolin, Helen E., Rodriguez-Rodriguez, Noe, Sivasubramaniam, Meera, Pannell, Richard, Cruickshank, James, Daly, Maria, Haim-Vilmovsky, Liora, Teichmann, Sarah A., McKenzie, Andrew N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642165/
https://www.ncbi.nlm.nih.gov/pubmed/31128961
http://dx.doi.org/10.1016/j.immuni.2019.05.002