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Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow
Innate lymphoid cells (ILCs) play strategic roles in tissue homeostasis and immunity. ILCs arise from lymphoid progenitors undergoing lineage restriction and the development of specialized ILC subsets. We generated “5x polychromILC” transcription factor reporter mice to delineate ILC precursor state...
Autores principales: | Walker, Jennifer A., Clark, Paula A., Crisp, Alastair, Barlow, Jillian L., Szeto, Aydan, Ferreira, Ana C.F., Rana, Batika M.J., Jolin, Helen E., Rodriguez-Rodriguez, Noe, Sivasubramaniam, Meera, Pannell, Richard, Cruickshank, James, Daly, Maria, Haim-Vilmovsky, Liora, Teichmann, Sarah A., McKenzie, Andrew N.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642165/ https://www.ncbi.nlm.nih.gov/pubmed/31128961 http://dx.doi.org/10.1016/j.immuni.2019.05.002 |
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