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A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

Current seasonal influenza virus vaccines only provide limited, short-lived protection, and antigenic drift in the hemagglutinin surface glycoprotein necessitates their annual re-formulation and re-administration. To overcome these limitations, universal vaccine strategies that aim at eliciting broa...

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Detalles Bibliográficos
Autores principales: Broecker, Felix, Liu, Sean T. H., Suntronwong, Nungruthai, Sun, Weina, Bailey, Mark J., Nachbagauer, Raffael, Krammer, Florian, Palese, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642189/
https://www.ncbi.nlm.nih.gov/pubmed/31341648
http://dx.doi.org/10.1038/s41541-019-0126-4