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Monoclonal Antibodies Against Human Papillomavirus E6 and E7 Oncoproteins Inhibit Tumor Growth in Experimental Cervical Cancer

Nearly all cases of cervical cancer are initiated by persistent infection with high-risk strains of human papillomavirus (hr-HPV). When hr-HPV integrates into the host genome, the constitutive expression of oncogenic HPV proteins E6 and E7 function to disrupt p53 and retinoblastoma regulation of cel...

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Detalles Bibliográficos
Autores principales: Jiang, Zewei, Albanese, Joseph, Kesterson, Joshua, Warrick, Joshua, Karabakhtsian, Rouzan, Dadachova, Ekaterina, Phaëton, Rébécca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642219/
https://www.ncbi.nlm.nih.gov/pubmed/31325765
http://dx.doi.org/10.1016/j.tranon.2019.06.003