Crystallized but not soluble uric acid elicits pro-inflammatory response in short-term whole blood cultures from healthy men

Several epidemiological studies have pointed at serum uric acid (SUA) as an independent risk factor for mortality, diabetes, hypertension, cardiovascular and kidney disease; however, no clear pathogenic pathway is established. Uric acid (UA) crystals show pro-inflammatory properties and can thus cre...

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Detalles Bibliográficos
Autores principales: Brovold, Henrik, Lund, Trine, Svistounov, Dmitri, Solbu, Marit D., Jenssen, Trond G., Ytrehus, Kirsti, Zykova, Svetlana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642259/
https://www.ncbi.nlm.nih.gov/pubmed/31324844
http://dx.doi.org/10.1038/s41598-019-46935-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642259/
https://www.ncbi.nlm.nih.gov/pubmed/31324844
http://dx.doi.org/10.1038/s41598-019-46935-w

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