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AKAP6 and phospholamban colocalize and interact in HEK‐293T cells and primary murine cardiomyocytes
Phospholamban (PLN) is an important Ca(2+) modulator at the sarcoplasmic reticulum (SR) of striated muscles. It physically interacts and inhibits sarcoplasmic reticulum Ca(2+) ATPase (SERCA2) function, whereas a protein kinase A (PKA)‐dependent phosphorylation at its serine 16 reverses the inhibitio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642276/ https://www.ncbi.nlm.nih.gov/pubmed/31325238 http://dx.doi.org/10.14814/phy2.14144 |