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Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response
BACKGROUND: Sphingomyelin synthase 1 (SMS1) has been reported to participate in hepatitis and atherosclerosis. However, its role in autoimmune response is not clear. This study investigates the possible involvement of SMS1 in B-cell activation and lupus-like autoimmunity. METHODS: SMS1 knockout lupu...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642282/ https://www.ncbi.nlm.nih.gov/pubmed/31262710 http://dx.doi.org/10.1016/j.ebiom.2019.06.038 |