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Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response

BACKGROUND: Sphingomyelin synthase 1 (SMS1) has been reported to participate in hepatitis and atherosclerosis. However, its role in autoimmune response is not clear. This study investigates the possible involvement of SMS1 in B-cell activation and lupus-like autoimmunity. METHODS: SMS1 knockout lupu...

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Detalles Bibliográficos
Autores principales:	Wang, Chenqiong, Ming, Bingxia, Wu, Xuefen, Wu, Tong, Cai, Shaozhe, Hu, Peng, Tang, Jungen, Tan, Zheng, Liu, Chaohong, Zhong, Jixin, Zheng, Fang, Dong, Lingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642282/ https://www.ncbi.nlm.nih.gov/pubmed/31262710 http://dx.doi.org/10.1016/j.ebiom.2019.06.038

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