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Vitamin D(3)-vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by emphysema and/or obstructive bronchiolitis. Deficiency in vitamin D(3) (VD3), which regulates gene expression through binding to vitamin D receptor (VDR), is associated with high risks of COPD susceptibility. Alveolar macro...
Autores principales: | Hu, Guangan, Dong, Ting, Wang, Sisi, Jing, Hongyu, Chen, Jianzhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642288/ https://www.ncbi.nlm.nih.gov/pubmed/31278070 http://dx.doi.org/10.1016/j.ebiom.2019.06.039 |
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