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Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy

Selective autophagy recycles damaged organelles and clears intracellular pathogens to prevent their aberrant accumulation. How ULK1 kinase is targeted and activated during selective autophagic events remains to be elucidated. In this study, we used chemically inducible dimerization (CID) assays in t...

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Detalles Bibliográficos
Autores principales: Vargas, Jose Norberto S., Wang, Chunxin, Bunker, Eric, Hao, Ling, Maric, Dragan, Schiavo, Giampietro, Randow, Felix, Youle, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642318/
https://www.ncbi.nlm.nih.gov/pubmed/30853401
http://dx.doi.org/10.1016/j.molcel.2019.02.010