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PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness

BACKGROUND: Our previous study revealed that PLAGL2 or POFUT1 can promote tumorigenesis and maintain significant positive correlations in colorectal cancer (CRC). However, the mechanism leading to the co-expression and the underlying functional and biological implications remain unclear. METHODS: Cl...

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Detalles Bibliográficos
Autores principales: Li, Daojiang, Lin, Changwei, Li, Nanpeng, Du, Yuheng, Yang, Chunxing, Bai, Yang, Feng, Zhicai, Su, Chen, Wu, Runliu, Song, Shenglei, Yan, Peicheng, Chen, Miao, Jain, Arad, Huang, Lihua, Zhang, Yi, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642334/
https://www.ncbi.nlm.nih.gov/pubmed/31279780
http://dx.doi.org/10.1016/j.ebiom.2019.06.051