RNA-guided piggyBac transposition in human cells

Safer and more efficient methods for directing therapeutic genes to specific sequences could increase the repertoire of treatable conditions. Many current approaches act passively, first initiating a double-stranded break, then relying on host repair to uptake donor DNA. Alternatively, we delivered...

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Detalles Bibliográficos
Autores principales: Hew, Brian E, Sato, Ryuei, Mauro, Damiano, Stoytchev, Ilko, Owens, Jesse B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642342/
https://www.ncbi.nlm.nih.gov/pubmed/31355344
http://dx.doi.org/10.1093/synbio/ysz018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642342/
https://www.ncbi.nlm.nih.gov/pubmed/31355344
http://dx.doi.org/10.1093/synbio/ysz018

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