Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank

BACKGROUND: High circulating low-density lipoprotein cholesterol (LDL-C) is a major risk factor for atherosclerosis and age-associated cardiovascular events. Long-term dyslipidaemia could contribute to the development of frailty in older individuals through its role in determining cardiovascular hea...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Wang, Yunzhang, Lehto, Kelli, Pedersen, Nancy L., Williams, Dylan M., Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642403/
https://www.ncbi.nlm.nih.gov/pubmed/31300347
http://dx.doi.org/10.1016/j.ebiom.2019.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642403/
https://www.ncbi.nlm.nih.gov/pubmed/31300347
http://dx.doi.org/10.1016/j.ebiom.2019.07.007

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