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Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

Light-sensitive G protein-coupled receptors (GPCRs)—rhodopsins—absorb photons to isomerize their covalently bound retinal, triggering conformational changes that result in downstream signaling cascades. Monostable rhodopsins release retinal upon isomerization as opposed to the retinal in bistable rh...

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Detalles Bibliográficos
Autores principales: Varma, Niranjan, Mutt, Eshita, Mühle, Jonas, Panneels, Valérie, Terakita, Akihisa, Deupi, Xavier, Nogly, Przemyslaw, Schertler, Gebhard F. X., Lesca, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642406/
https://www.ncbi.nlm.nih.gov/pubmed/31249143
http://dx.doi.org/10.1073/pnas.1902192116