Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling

BACKGROUND: Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia (SMA) pathogenesis in Kenyan children discovered that novel LAIR1 g...

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Detalles Bibliográficos
Autores principales: Achieng, Angela O., Guyah, Bernard, Cheng, Qiuying, Ong'echa, John M., Ouma, Collins, Lambert, Christophe G., Perkins, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642411/
https://www.ncbi.nlm.nih.gov/pubmed/31257148
http://dx.doi.org/10.1016/j.ebiom.2019.06.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642411/
https://www.ncbi.nlm.nih.gov/pubmed/31257148
http://dx.doi.org/10.1016/j.ebiom.2019.06.040

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