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IL-6 and IL-8 secreted by tumour cells impair the function of NK cells via the STAT3 pathway in oesophageal squamous cell carcinoma

BACKGROUND: Recurrence and metastasis are the leading causes of tumour-related death in patients with oesophageal squamous cell carcinoma (ESCC). Tumour-infiltrating natural killer cells (NK cells) display powerful cytotoxicity to tumour cells and play a pivotal role in tumour therapy. However, the...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Gao, Feng-xia, Wang, Chao, Qin, Mei, Han, Fei, Xu, Tao, Hu, Zhi, Long, Yang, He, Xue-mei, Deng, Xin, Ren, De-lian, Dai, Tian-yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642486/
https://www.ncbi.nlm.nih.gov/pubmed/31324197
http://dx.doi.org/10.1186/s13046-019-1310-0