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Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells

BACKGROUND: Acquired resistance remains a limitation of the clinical use of 5-fluorouracil (5-FU). Because exosomes, are important vesicles participating in intercellular communication, their contribution to the development of acquired 5-FU resistance needs to be elucidated. In this study, we aimed...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Liu, Rui-Xian, Chan, Ka-Wo, Hu, Jiancong, Zhang, Jingdan, Wei, Lili, Tan, Huiliu, Yang, Xiangling, Liu, Huanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642525/
https://www.ncbi.nlm.nih.gov/pubmed/31324203
http://dx.doi.org/10.1186/s13046-019-1314-9