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MiR-34a affects dexmedetomidine-inhibited chronic inflammatory visceral pain by targeting to HDAC2

BACKGROUND: Dexmedetomidine (DEX) has been used as an anesthetic for decades. The present investigation aimed to elucidate the analgesic impact of DEX on 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced chronic inflammatory visceral pain (CIVP) in rats. METHODS: TNBS with or without DEX to Male Spr...

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Detalles Bibliográficos
Autores principales: Liang, Meng, Shao, Aijie, Tang, Xinsheng, Feng, Meiling, Wang, Jing, Qiu, Yingna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642536/
https://www.ncbi.nlm.nih.gov/pubmed/31324142
http://dx.doi.org/10.1186/s12871-019-0801-z